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Severe adhesive small bowel obstruction

Salomone Di Saverio, Fausto Catena, Michael D. Kelly, Gregorio Tugnoli, Luca Ansaloni

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 436-439 doi: 10.1007/s11684-012-0221-7

Abstract:

Adhesive small bowel obstruction is a frequent cause of hospital admission.A 58-year-old patient was operated for extensive adhesive small bowel obstruction after having had twosmall bowel obstruction.For patients admitted several times for adhesive small bowel obstruction, the relative risk of recurringSeveral strategies for non-operative conservative management of adhesive small bowel obstruction have

Keywords： post-operative intraperitoneal adhesions     adhesive small bowel obstruction     adhesiolysis     antiadhesion treatments    

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A ruptured recurrent small bowel gastrointestinal stromal tumour causing hemoperitoneum

Eric C.H. Lai,Kam Man Chung,Stephanie H.Y. Lau,Wan Yee Lau

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 108-111 doi: 10.1007/s11684-014-0344-0

Abstract: intra-abdominal recurrence from a previously resected gastrointestinal stromal tumour (GIST) of the smallbowel, and the patient presented with hemoperitoneum.In this patient who presented with spontaneous rupture of a small intestinal GIST, the novel use of targeted

Keywords： gastrointestinal stromal tumour     hemoperitoneum     small bowel GIST     small bowel neoplasm     imatinib    

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Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 239-248 doi: 10.1007/s11684-018-0617-0

Abstract: In fact, several studies indicated that acute and chronic allograft rejection in small bowel transplantation

Keywords： gut microbiota     small bowel transplantation     acute rejection     chronic rejection     mucosal immunity     biomarker    

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On the applicability of different adhesion models in adhesive particulate flows

Guanqing LIU, Shuiqing LI, Qiang YAO,

Frontiers in Energy 2010, Volume 4, Issue 2,   Pages 280-286 doi: 10.1007/s11708-009-0062-5

Abstract: provides quantitative criteria for the appropriate selection of adhesion models applicable to a specific adhesive

Keywords： adhesive contact     van der Waals force     adhesion model     adhesion map     DEM    

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Learning from biological attachment devices: applications of bioinspired reversible adhesive methods

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 3, doi: 10.1007/s11465-022-0699-x

Abstract: From nanoscale to macroscale, each type of adhesive organ has its own underlying mechanisms.Many biological adhesive mechanisms have been studied and can be incorporated into robot designs.This paper presents a systematic review of reversible biological adhesive methods and the bioinspiredThe study discussed how biological adhesive methods, such as dry adhesion, wet adhesion, mechanical adhesionThe morphology of typical adhesive organs, as well as the corresponding attachment models, is highlighted

Keywords： adhesion     bioinspired attachment     biomimetic gripper     climbing robot    

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Towards Cr(VI)-free anodization of aluminum alloys for aerospace adhesive bonding applications: A review

Shoshan T. Abrahami, John M. M. de Kok, Herman Terryn, Johannes M. C. Mol

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 3,   Pages 465-482 doi: 10.1007/s11705-017-1641-3

Abstract: For more than six decades, chromic acid anodizing (CAA) has been the central process in the surface pre-treatment of aluminum for adhesively bonded aircraft structures. Unfortunately, this electrolyte contains hexavalent chromium (Cr(VI)), a compound known for its toxicity and carcinogenic properties. To comply with the new strict international regulations, the Cr(VI)-era will soon have to come to an end. Anodizing aluminum in acid electrolytes produces a self-ordered porous oxide layer. Although different acids can be used to create this type of structure, the excellent adhesion and corrosion resistance that is currently achieved by the complete Cr(VI)-based process is not easily matched. This paper provides a critical overview and appraisal of proposed alternatives to CAA, including combinations of multiple anodizing steps, pre- and post anodizing treatments. The work is presented in terms of the modifications to the oxide properties, such as morphological features (e.g., pore size, barrier layer thickness) and surface chemistry, in order to evaluate the link between fundamental principles of adhesion and bond performance.

Keywords： aluminum     Cr(VI)-free     surface pre-treatments     anodizing     adhesive bonding    

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Treatment of infant postrenal acute renal failure following obstruction due to upper urinary calculi

Hui-Xia ZHOU MD, Zhi-Chun FENG MD, Hao MENG MD, Xiao-Guang ZHOU MD, Shuang LI BM, Jun WANG MM, Shi-Xi DAI BM,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 127-130 doi: 10.1007/s11684-010-0009-6

Abstract: The surgical emergency treatments and curative effects of postrenal acute renal failure following obstructionOf the 13 infants with postrenal acute renal failure following obstruction due to upper urinary calculiureteroscopy is a minimally invasive, safe and effective therapy for postrenal acute renal failure following obstructionFor those infants whose urethras are thin and small, the open ureterolithotomy is a suitable method.

Keywords： infant     acute renal failure     postrenal     ureteroscopy    

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Simulation and experimental improvement on a small-scale Stirling thermo-acoustic engine

Mao CHEN,Yonglin JU

Frontiers in Energy 2016, Volume 10, Issue 1,   Pages 37-45 doi: 10.1007/s11708-015-0390-6

Abstract: In this paper, the influence of the dimensions of the main parts of the small-scale Stirling thermo-acousticBased on the numerical simulation, a small-scale Stirling thermo-acoustic engine were constructed and

Keywords： thermo-acoustic Stirling engine     small-scale     simulation     experiment    

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Discovery of small molecule degraders for modulating cell cycle

Frontiers of Medicine   Pages 823-854 doi: 10.1007/s11684-023-1027-5

Abstract: The cell cycle is a complex process that involves DNA replication, protein expression, and cell division. Dysregulation of the cell cycle is associated with various diseases. Cyclin-dependent kinases (CDKs) and their corresponding cyclins are major proteins that regulate the cell cycle. In contrast to inhibition, a new approach called proteolysis-targeting chimeras (PROTACs) and molecular glues can eliminate both enzymatic and scaffold functions of CDKs and cyclins, achieving targeted degradation. The field of PROTACs and molecular glues has developed rapidly in recent years. In this article, we aim to summarize the latest developments of CDKs and cyclin protein degraders. The selectivity, application, validation and the current state of each CDK degrader will be overviewed. Additionally, possible methods are discussed for the development of degraders for CDK members that still lack them. Overall, this article provides a comprehensive summary of the latest advancements in CDK and cyclin protein degraders, which will be helpful for researchers working on this topic.

Keywords： PROTAC     molecular glue     degrader     cell cycle     CDK     cyclin    

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Fine-tuning cell organelle dynamics during mitosis by small GTPases

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 339-357 doi: 10.1007/s11684-022-0926-1

Abstract: Small GTPases belonging to the Ras superfamily regulate various cell organelles during division.Being the key regulators of membrane dynamics, the dysregulation of small GTPases is widely associatedRecent discoveries shed light on the molecular properties of small GTPases as sophisticated modulatorsThis review collects current knowledge on small GTPases in the regulation of cell organelles during mitosisand highlights the mediator role of small GTPase in transducing cell cycle signaling to organelle dynamics

Keywords： small GTPase     cell organelle     mitosis    

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Calculating frictional force with considering material microstructure and potential on contact surfaces

XU Zhongming, HUANG Ping

Frontiers of Mechanical Engineering 2007, Volume 2, Issue 4,   Pages 474-477 doi: 10.1007/s11465-007-0082-y

Abstract: The potential change can be gained by a universal adhesive energy function.

Keywords： coefficient     dissipation mechanism     universal adhesive     interfacial     Independent Oscillator    

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Molecular classification of non-small-cell lung cancer: diagnosis, individualized treatment, and prognosis

Yue Yu, Jie He

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 157-171 doi: 10.1007/s11684-013-0272-4

Abstract:

Non-small-cell lung cancer (NSCLC) is the most common cause of premature death among the malignant

Keywords： non-small-cell lung cancer     molecular typing     individualized medicine     molecular-targeted therapy     gene expression    

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Performance prediction of switched reluctance generator with time average and small signal models

Jyoti KOUJALAGI, B. UMAMAHESWARI, R. ARUMUGAM

Frontiers in Energy 2013, Volume 7, Issue 1,   Pages 56-68 doi: 10.1007/s11708-012-0216-8

Abstract: mathematical model and predicts the performance of switched reluctance generator with time average and smallFinally, to track control voltage and current wave shapes, a small signal model is designed.

Keywords： generator     reluctance     switching model     small signal model     time average model    

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Treatment of advanced non-small cell lung cancer with driver mutations: current applications and future

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 18-42 doi: 10.1007/s11684-022-0976-4

Abstract: With the improved understanding of driver mutations in non-small cell lung cancer (NSCLC), expanding

Keywords： non-small cell lung cancer     driver mutations     treatment strategy     resistant mechanism     immune-checkpoint    

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Engineering Protein Coacervates into a Robust Adhesive for Real-Time Skin Healing Article

Ming Li, Baimei Liu, Wei Xu, Lai Zhao, Zili Wang, Haonan He, Jingjing Li, Fan Wang, Chao Ma, Kai Liu, Hongjie Zhang

Engineering 2023, Volume 31, Issue 12,   Pages 76-85 doi: 10.1016/j.eng.2023.07.013

Abstract: However, it is a grand challenge for current adhesive systems to achieve robust adhesion due to theirHerein, an extracellular matrix-derived biocomposite adhesive with robust adhesion and a real-time skinLiquid–liquid phase separation is well-harnessed to drive the assembly of the biocomposite adhesive    Moreover, the engineered bioderived components endow this adhesive material with biocompatibility

Keywords： Biocomposite adhesive     Protein     DNA     Coacervates     Skin healing    

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Title Author Date Type Operation

Severe adhesive small bowel obstruction

Salomone Di Saverio, Fausto Catena, Michael D. Kelly, Gregorio Tugnoli, Luca Ansaloni

Journal Article

A ruptured recurrent small bowel gastrointestinal stromal tumour causing hemoperitoneum

Eric C.H. Lai,Kam Man Chung,Stephanie H.Y. Lau,Wan Yee Lau

Journal Article

Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Journal Article

On the applicability of different adhesion models in adhesive particulate flows

Guanqing LIU, Shuiqing LI, Qiang YAO,

Journal Article

Learning from biological attachment devices: applications of bioinspired reversible adhesive methods

Journal Article

Towards Cr(VI)-free anodization of aluminum alloys for aerospace adhesive bonding applications: A review

Shoshan T. Abrahami, John M. M. de Kok, Herman Terryn, Johannes M. C. Mol

Journal Article

Treatment of infant postrenal acute renal failure following obstruction due to upper urinary calculi

Hui-Xia ZHOU MD, Zhi-Chun FENG MD, Hao MENG MD, Xiao-Guang ZHOU MD, Shuang LI BM, Jun WANG MM, Shi-Xi DAI BM,

Journal Article

Simulation and experimental improvement on a small-scale Stirling thermo-acoustic engine

Mao CHEN,Yonglin JU

Journal Article

Discovery of small molecule degraders for modulating cell cycle

Journal Article

Fine-tuning cell organelle dynamics during mitosis by small GTPases

Journal Article

Calculating frictional force with considering material microstructure and potential on contact surfaces

XU Zhongming, HUANG Ping

Journal Article

Molecular classification of non-small-cell lung cancer: diagnosis, individualized treatment, and prognosis

Yue Yu, Jie He

Journal Article

Performance prediction of switched reluctance generator with time average and small signal models

Jyoti KOUJALAGI, B. UMAMAHESWARI, R. ARUMUGAM

Journal Article

Treatment of advanced non-small cell lung cancer with driver mutations: current applications and future

Journal Article

Engineering Protein Coacervates into a Robust Adhesive for Real-Time Skin Healing

Ming Li, Baimei Liu, Wei Xu, Lai Zhao, Zili Wang, Haonan He, Jingjing Li, Fan Wang, Chao Ma, Kai Liu, Hongjie Zhang

Journal Article